RD TOCRIS一级代理,Z-Guggulsterone供应CAS号39025-23-5
- 产品型号: 3570
- 简单描述
- RD TOCRIS一级代理,Z-Guggulsterone供应CAS号39025-23-5我公司代理RD产品和tocris产品Z-Guggulsterone货号:3570规格:10mg,50mg
RD TOCRIS一级代理,Z-Guggulsterone供应CAS号39025-23-5
Catalog Number: 3570
Chemical Name: (Z)-Pregna-4,17(20)-diene-3,16-dione
详细产品信息:
Biological Activity
Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo. More active isomer of guggulsterone (Cat. No. 2013).
Technical Data
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M.Wt:
312.45
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Formula:
C21H28O2
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Solubility:
Soluble to 20 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming
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Purity:
>98%
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Storage:
Store at RT
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CAS No:
39025-23-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.