miltenyi美天旎Human IL-2 IS细胞因子130-097-748

miltenyi美天旎Human IL-2 IS细胞因子

  • 产品型号:  130-097-748
  • 简单描述
  • miltenyi美天旎Human IL-2 IS细胞因子品牌:Miltenyi(美天旎)货号:130-097-748CAS号:详见说明书供应商:Miltenyi(美天旎)保质期:详见说明书保存条件:详见说明书规格:EA
详细介绍

miltenyi美天旎Human IL-2 IS细胞因子miltenyi美天旎Human IL-2 IS细胞因子

IL-2 IS stands for interleukin 2 “Improved Sequence”, also termed aldesleukin, and is a variant of IL-2 with a serine to cysteine substitution. Human IL-2 IS is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays, and possesses the same properties as naturally occurring IL-2.

Background information

IL-2, a potent lymphoid cell growth factor, is a typical four α-helix bundle cytokine. It is produced by activated T cells, especially the CD4+ T helper cell population. It plays an important role in both the activation and maintenance of immune responses and in lymphocyte development. IL-2 promotes proliferation and differentiation of T cells, NK cells and B cells and is involved in the elimination of self-reactive T cells. IL-2 signals through a receptor complex consisting of IL-2 receptor α-chain (CD25), β- chain, and common γ-chain. The latter two are also used for IL-15 signaling.

Biological activity

Proliferation of CTLL-2 cells (NIBSC 86/504)

research grade: ≥ 3×106 IU/mg

premium grade: ≥ 5×106 IU/mg

Quality description

Research-grade cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Premium-grade cytokines offer the convenience of high and well-defined biological activities and allow exact unit dosing for demanding applications. The biological activity is determined after lyophilization and reconstitution, and normalized to WHO/NIBSC standards whenever available. In general, endotoxin levels are <0.01 ng/μg (<0.1 EU/μg), and purities are >97%. Lot-specific certificates of analysis are available on request (macstec@miltenyibiotec.de).

miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子130-095-765

miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子

  • 产品型号:  130-095-765
  • 简单描述
  • miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子IL-15 stands for interleukin 15. Human IL-15 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.
详细介绍

miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子,miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子,

igure 1

miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子130-095-765miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子130-095-765

Human IL-15 activity assay. The biological activity of Human IL-15 is determined by proliferation assay using CTLL2 cells.

Figure 2

miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子130-095-765miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子130-095-765

SDS-PAGE of Human IL-15, premium grade under reduced (R) and non-reduced (NR) conditions.

Figure 3

miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子130-095-765miltenyi美天旎human IL-15蛋白,人白介15细胞生长因子130-095-765

Mass spectrometry analysis (ESI-MS) of Human IL-15, premium grade. The peak corresponds to the calculated molecular mass of 1277

 

订购货号:130-095-765

miltenyi美天旎CD34分选磁珠human Diamond CD34 Isolation Ki130-094-531

miltenyi美天旎CD34分选磁珠human Diamond CD34 Isolation Ki

  • 产品型号:  130-094-531
  • 简单描述
  • miltenyi美天旎CD34分选磁珠human Diamond CD34 Isolation Kit品牌:Miltenyi(美天旎)货号:130-094-531CAS号:详见说明书供应商:Miltenyi(美天旎)保质期:详见说明书保存条件:详见说明书规格:EAmiltenyi 美天旎 磁珠及其他分选产品 130-094-531 Diamond CD34 Isol
详细介绍

miltenyi美天旎CD34分选磁珠human Diamond CD34 Isolation Kitmiltenyi美天旎CD34分选磁珠human Diamond CD34 Isolation Kitt

 

品牌: Miltenyi(美天旎)
货号: 130-094-531
CAS号: 详见说明书
供应商: Miltenyi(美天旎)
保质期: 详见说明书
保存条件: 详见说明书
规格: EA

miltenyi 美天旎 磁珠及其他分选产品 130-094-531 Diamond CD34 Isolation Kit, human

 

 

The Diamond CD34 Isolation Kit has been specifically developed for the isolation of highly pure LinCD34+ hematopoietic stem cells from peripheral blood1, bone marrow2,3 or cord blood.

订购信息:

Diamond CD34 Isolation Kit, human

Capacity: for 2×109 total cells

Data sheet

  130-094-531 price on request here

DAKO丹科human Lambda Light Chains现货供应A0193

DAKO丹科human Lambda Light Chains现货供应

  • 产品型号:  A0193
  • 简单描述
  • DAKO丹科human Lambda Light Chains现货供应产品类型 : 抗体产品名称 : Lambda Light Chains目录 : A0193克隆性 : 多克隆宿主 : 兔
详细介绍

DAKO丹科human Lambda Light Chains现货供应DAKO丹科human Lambda Light Chains现货供应

产品类型 :抗体

产品名称 :Lambda Light Chains

目录 :A0193

克隆性 :多克隆

宿主 :兔

The antigen used for immunization is a pool of human lambda Bence Jones proteins. Therefore, a reagent with a particularly wide specificity for lambda-chains is obtained. The specificity is directed against surface as well as hidden determinants and has been ascertained by gel precipitation techniques and immunohistochemistry.
A0193 is excellent for the typing of free and bound monoclonal lambda-chains by immunoelectrophoresis and immunofixation.

Key Features

  • Excellent specificity and precipitation ability
  • High lot to lot consistency
  • Optimized for a variety of applications with validated protocols
  • Certified manufacturing facilities guarantee full quality control

Dako's products are the result of almost 50 years experience ensuring quality and innovation in antibodies and reagents.

miltenyi美天旎human CD138 MicroBeads磁珠微球130-051-301

miltenyi美天旎human CD138 MicroBeads磁珠微球

  • 产品型号:  130-051-301
  • 简单描述
  • 品牌:Miltenyi Biotec货号:130-051-301miltenyi美天旎human CD138 MicroBeads磁珠微球抗体名:CD138 MicroBeads, human抗体英文名:CD138 MicroBeads, human靶点:详询浓度:详询应用范围:详询
详细介绍

miltenyi美天旎human CD138 MicroBeads磁珠微球miltenyi美天旎human CD138 MicroBeads磁珠微球

CD138 MicroBeads were developed for the positive selection or depletion of plasma cells from PBMCs, bone marrow, leukapheresis harvests, and single-cell suspensions from lymphoid tissues.

Product   Order no. Price  

CD138 MicroBeads, human

Capacity: for 2×109 total cells

Data sheet

  130-051-301 price on request here  

CD138 MicroBeads, human – lyophilized

Capacity: for 2×109 total cells

Data sheet

  130-097-614 price on request here  

CD138 MicroBeads + CD138-PE, human

Capacity: for 2×109 total cells

Data sheet

  130-090-503 price on request here  

 

DAKO丹科anti-human Kappa Light Chains抗体A0191

DAKO丹科anti-human Kappa Light Chains抗体

  • 产品型号:  A0191
  • 简单描述
  • DAKO丹科anti-human Kappa Light Chains抗体公司名称 : 丹科医疗DAKO产品类型 : 抗体产品名称 : Kappa Light Chains目录 : A0191克隆性 : 多克隆宿主 : 兔
详细介绍

DAKO丹科anti-human Kappa Light Chains抗体

DAKO抗体是丹麦的著名抗体生产商,提供世界上质量zui稳定,zui为经典的抗体。其主要产品涉及免疫化学、流式细胞,免疫组织化学,原位杂交,微生物检验等。DAKO的不同显色系统,Envision,LSAB和免疫细胞化学的CAS,GenpointTM和用于分子病理学的PNA=ISH试剂盒,和用于ELISA的AMPAKTM/AmpliQ是其在生物化学研究中的革新产品 。

DAKO丹科anti-human Kappa Light Chains抗体

Kappa Light Chains (Multipurpose)

 

DAKO丹科anti-human Kappa Light Chains抗体A0191

These reagents have been produced in a manner that ensures a particularly wide specificity for kappa-chains. The specificity is directed against surface as well as hidden determinants and has been ascertained by gel precipitation techniques and immunohistochemistry.

A0191 is excellent for the typing of free and bound monoclonal kappa-chains by immunoelectrophoresis and immunofixation.

现货供应中!

invitrogen novex Human Aβ40 ELISA Kit现货 KHB3481

invitrogen novex Human Aβ40 ELISA Kit现货 上海金畔

  • 产品型号:  KHB3481
  • 简单描述
  • invitrogen novex Human Aβ40 ELISA Kit现货 上海金畔人 Aβ40 ELISA 试剂盒能在组织培养基、组织匀浆、脑脊液中,选择性地定量天然和重组Aβ40(Beta淀粉质40)。这一试剂盒不能检测Aβ42/Aβ43。它是Cat. Nos. 88348/89348的替代产品。
详细介绍

invitrogen novex Human Aβ40 ELISA Kit现货 上海金畔

人Aβ40 ELISA 试剂盒包括以下试剂、缓冲液和:

• Aβ40 抗体包被板
• Aβ42检测抗体
• HRP-偶联抗兔IgG抗体
• Aβ40 冻干标准品
• 稳定的色原体
• 洗涤缓冲液
• 洗脱缓冲液
• 稀释缓冲液
• 反应终止溶液
• 板盖

invitrogen novex Human Aβ40 ELISA Kit现货 上海金畔

人 Aβ40 ELISA 试剂盒能在组织培养基、组织匀浆、脑脊液中,选择性地定量天然和重组Aβ40(Beta淀粉质40)。这一试剂盒不能检测Aβ42/Aβ43。它是Cat. Nos. 88348/89348的替代产品。人 Aβ40 ELISA 试剂盒仅供科研,不可用于人或动物的治疗或诊断。

• 易用的夹心式ELISA
• 通常在一天内获得结果,快捷的4小时温育操作流程
• 精度 -<10% CV 板内和板间 
• 预包被的可拆卸8孔板条
• 严格验证

invitrogen novex Human Aβ40 ELISA Kit现货 上海金畔

人Aβ40 ELISA 试剂盒为固相夹心型、酶联免疫吸附测定试剂(ELISA)。人AβNH-2末端区域特异性结合的单克隆抗体被预包被在所提供的微孔板的孔内。在*次温育时,标准品、对照品以及未知样品被点入孔内,与特异性结合Aβ1-40序列中COOH末端的兔抗体一起温育。使用辣根过氧化物酶标记的抗-兔抗体来检测结合的兔抗体。洗涤后,加入辣根过氧化物酶标记的抗-兔抗体。经过第二次孵育以及洗涤未结合的酶之后,加入底物溶液,它与结合的酶作用之后可以产生颜色。这种有色产物的强度与原样品中人Aβ42的浓度是正相关的。样品中Aβ40的浓度是通过试剂盒内重组Aβ40标准品的反应标准曲线进行定量(图1)。

一般在一天之内获得结果,快捷的4小时温育方案
。试剂盒已将抗体预包被到微孔内,您无需自己制板。无需过夜温育。温育步骤可在4小时内完成。

精度 -<10% CV 板内和板间
该试剂盒的精度经过验证,可确保板内、板间以及批次之间结果*(图2)。

严格验证
每一个InvitrogenELISA试剂盒都经过灵敏度、特异性以及批次之间重复性的验证。参考使用说明中更多关于验证的信息。

经济的可拆卸板
预包被的可拆卸8孔板条,使您能轻松调整所需的样品量。如果您选择在一次实验内不对整块板进行检测,每块板上的两个标准品覆孔使您能够调整新的覆孔。

 

LIFE novex Aβ42 Human ELISA Kit货号KHB3441

LIFE novex Aβ42 Human ELISA Kit货号KHB3441 上海金畔

  • 产品型号:  
  • 简单描述
  • LIFE novex Aβ42 Human ELISA Kit货号KHB3441 上海金畔人Aβ42 ELISA试剂盒能在组织培养基、组织匀浆、脑脊液及其它样品中,选择性地定量天然和重组Aβ42。该试剂盒不能检测Aβ40/Aβ43。 它是货号88344/89344的替代产品。 人Aβ42 ELISA试剂盒仅供研究使用。不得用于人或动物的治疗或诊断。
详细介绍

LIFE novex Aβ42 Human ELISA Kit货号KHB3441 上海金畔

本试剂盒特点:

• 易用夹心式ELISA
• 通常在一天内获得结果——快速的4小时孵育实验方案
• 动态范围广 – 7.1-1000 pg/ml
• 预包被、可拆卸8联反应管
• 严格验证

LIFE novex Aβ42 Human ELISA Kit货号KHB3441 上海金畔

人Aβ42 ELISA试剂盒包括下列试剂、缓冲液和:

• Aβ42抗体包被板
• Aβ42检测抗体
• HRP-偶联抗兔IgG抗体
• Aβ40冻干标准品
• 稳定色原体
• 洗涤缓冲液
• 稀释缓冲液
• 终止液
• 反应板盖

LIFE novex Aβ42 Human ELISA Kit货号KHB3441 上海金畔

易用夹心式ELISA
人Aβ42试剂盒是固相夹心型酶联免疫吸附测定 (ELISA)。人Aβ NH2末端区域特异性结合的单克隆抗体被预包被在所提供的微孔板条内。在*次孵育时,将标准品、对照品和未知样品移至孔内,与特异性结合1-42 Aβ 序列中COOH末端的兔抗体一起孵育。使用辣根过氧化物酶标记的抗兔抗体来检测结合的兔抗体。洗涤后,加入辣根过氧化物酶标记的抗兔抗体 (酶)。经过第二次孵育并洗涤所有未结合的酶后,加入底物溶液,它与结合酶作用后可以产生颜色。这种有色产物的强度与原样品中的人Aβ42浓度直接呈正比。通过试剂盒内的重组Aβ42标准曲线定量样品 (图1)。

一般在一天内获得结果 – 快速的4小时孵育实验方案
试剂盒已将捕获抗体预包被到孔内,您无需自己包被反应板。无需过夜孵育。孵育步骤可在4小时内完成。

动态范围广 – 7.1-1000 pg/ml
该分析较广的动态范围使您无需估算样品落入线性分析范围所需的稀释比例 (图2)。

经济可拆卸孔
预包被的可拆卸8联管,使您能轻松调整所需的样品量。如果您选择在一次实验内不对整块反应板进行检测,每块板上的两个标准品孔使您能够调整新孔。

严格验证
每个Invitrogen ELISA试剂盒均已经过灵敏度、特异性和批次间*性验证。参见实验方案说明,了解更多验证信息。

Invitrogen ELISA试剂盒系列中的一员
Invitrogen拥有各种ELISA试剂盒,可用于疾病相关蛋白质的检测。这些优化ELISA试剂盒具有的灵敏度、可靠的特异性和稳定的性能,是您获得生理相关定量结果的良好选择。

 

Biolegend Human CD28单抗(细胞治疗级) 货号302914302913

Biolegend Human CD28单抗(细胞治疗级) 货号302914

  • 产品型号:  302913
  • 简单描述
  • Biolegend Human CD28单抗(细胞治疗级) 货号302914规格:302913 规格:50ug302914 规格:500ug302923 规格:1mg现货供应
详细介绍

Biolegend Human CD28单抗(细胞治疗级) 货号302914

通用名称:T淋巴细胞活化用抗人CD28单抗

Biolegend Human CD28单抗(细胞治疗级) 货号302914

CD28分子存在于大多数T细胞表面,被认为是一种T细胞*的表面分子。T细胞对抗原的反应性主要通过CD3/TCR复合物介导,但也有赖于T细胞表面其他分子的协同。CD28与其天然配基B7结合可发挥共刺激作用,作为第二信号介绍T细胞激活,促进T细胞增殖及分泌多种细胞因子并介绍导T,B细胞粘附。在体外T淋巴细胞激活扩增中抗人CD28单克隆抗体通过第二信号通路发挥共刺激作用。

简单信息:

Clone: CD28.2 (See other available formats)
Isotype: Mouse IgG1, κ
Isotype Control: LEAF™ Purified Mouse IgG1, κ Isotype Ctrl
Workshop
Number:
V-CD28.05
Reactivity: Human, Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Squirrel Monkey, Capuchin Monkey, Sooty Mangabey
Formulation: 0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.1 EU/µg of the protein (<0.01 ng/µg of the protein) as determined by the LAL test.
Preparation: The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration: 1.0 mg/ml

订购信息:

302913 规格:50ug
302914 规格:500ug
302923 规格:1mg

DAKO(丹科)Human Chromogranin A clone DAK-A3抗体M0869

DAKO(丹科)Human Chromogranin A clone DAK-A3抗体

  • 产品型号:  M0869
  • 简单描述
  • DAKO(丹科)Human Chromogranin A clone DAK-A3抗体Monoclonal Mouse Anti-HumanChromogranin AClone DAK-A3Labels cells of neuroendocrine origin. Anti-Chromogranin A, clone DAK-A3, reacts with an epitope o
详细介绍

DAKO(丹科)Human Chromogranin A clone DAK-A3抗体

DAKO抗体是丹麦的著名抗体生产商,提供世界上质量zui稳定,zui为经典的抗体。其主要产品涉及免疫化学、免疫组织化学,原位杂交,微生物检验,流式细胞,等。DAKO的不同显色系统,Envision,LSAB和免疫细胞化学的CAS,GenpointTM和用于分子病理学的PNA=ISH试剂盒,和用于ELISA的AMPAKTM/AmpliQ是其在生物化学研究中的革新产品 。

DAKO(丹科)Human Chromogranin A clone DAK-A3抗体

Isotype IgG2b, kappa

  • Frozen
  • Formalin
  • HIER

DAKO(丹科)Human Chromogranin A clone DAK-A3抗体

 

Monoclonal Mouse Anti-Human

Chromogranin A

Clone DAK-A3

Labels cells of neuroendocrine origin. Anti-Chromogranin A, clone DAK-A3, reacts with an epitope on the C-terminal half of the chromogranin A molecule. Results aid in the classification of neuroendocrine-derived tumors.

常备现货抗体,详细信息可和选购

 

Biolegend LEAF Purified Human CD28单抗302913302914

Biolegend LEAF Purified Human CD28单抗302913

  • 产品型号:  302914
  • 简单描述
  • Biolegend LEAF Purified Human CD28单抗302913302913 规格:50ug302914 规格:500ug302923 规格:1mg现货!
详细介绍

Biolegend LEAF Purified Human CD28单抗302913

Clone: CD28.2 (See other available formats)
Isotype: Mouse IgG1, κ
Isotype Control: LEAF™ Purified Mouse IgG1, κ Isotype Ctrl
Workshop
Number:
V-CD28.05
Reactivity: Human, Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Squirrel Monkey, Capuchin Monkey, Sooty Mangabey
Formulation: 0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.1 EU/µg of the protein (<0.01 ng/µg of the protein) as determined by the LAL test.
Preparation: The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration: 1.0 mg/ml

Biolegend LEAF Purified Human CD28单抗302913

Storage & Handling: The CD28 antibody solution should be stored undiluted between 2°C and 8°C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
Application: FC – Quality tested
Costim, IP, IHC – Reported in the literature
Recommended Usage: Each lot of this antibody is quality control tested byimmunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Application
Notes:
Additional reported applications (for the relevant formats) include: immunoprecipitation, immunohistochemical staining of acetone-fixed frozen tissue sections4, and in vitro T cell costimulation5-8. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The CD28.2 antibody co-stimulates T cell proliferation and cytokine production in the presence of suboptimal amounts of anti-CD3 antibody. The LEAF™ purified antibody (Endotoxin <0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 302914). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 302934) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).
Application
References:
1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. 
2. Nunes J, et al. 1993. Biochem. J. 293:835. 
3. Calea-Lauri J, et al. 1999. J. Immunol. 163:62.
4. Tazi A, et al. 1999. J. Immunol. 163:3511. (IHC)
5. Marti F, et al. 2001. J. Immunol. 166:197. (Costim)
6. Jeong SH, et al. 2004. J. Virol. 78:6995. (Costim)
7. Rivollier A, et al. 2004. Blood 104:4029. (Costim)
8. Scharschmidt E, et al. 2004. Mol. Cell Biol. 24:3860. (Costim)
9. Sheng W, et al. 2007.Elsevier 580:6819. PubMed
10. Mitsuhashi M. 2007. Clin Chem.53:148. PubMed
11. Ye Z, et al. 2008. Infect. Immun. 76:2541. PubMed
12. Magatti M, et al. 2008. Stem Cells 26:182. (FA) PubMed
  Publication Library
Biolegend LEAF Purified Human CD28单抗302913302914

Human peripheral blood lymphocytes stained with LEAF™ purified CD28.2, followed by anti-mouse IgGs FITC

Biolegend LEAF Purified Human CD28单抗302913302914

Human peripheral blood mononuclear cells were stained with CFSE on day 0, and then stimulated with (filled histogram) or without (open histogram) immobilized LEAF™ Purified CD3 (clone UCHT1) and LEAF™ purified CD28 (clone CD28.2) for 3 days. On day 4, cells were harvested and stained with CD4 Brilliant Violet 711™. Dot plot (above) was analyzed on live cells. Histogram data (below) was analyzed by gating on CD4 positive cells.

Biolegend LEAF Purified Human CD28单抗302913302914

Compare all formats

 

 
 

Antigen Details
 
Description: CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Other Names: T44, Tp44
Structure: Ig superfamily, type I transmembrane glycoprotein, homodimer, 44 kD
Distribution: Mature T cells, thymocytes, NK cell subsets, plasma cells, EBV-positive B cells
Function: T cell costimulation
Ligand Receptor: CD80, CD86
Antigen
References:
1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. 
2. June CH, et al. 1994. Immunol. Today 15:321. 
3. Linskey PS, et al. 1993. Annu. Rev. Immunol. 11:191.
GeneID: 940 Biolegend LEAF Purified Human CD28单抗302913302914
UniProt: View information about CD28 on UniProt.org
Keywords: LEAF™ Purified anti-human CD28, CD28.2, LEAF™, T44, Tp44, Human, Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Squirrel Monkey, Capuchin Monkey, Sooty Mangabey, Activation, Costimulation, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Biofunctional Assay, Immunology, Antibodies

订购信息:

302913 规格:50ug
302914 规格:500ug
302923 规格:1mg

现货*!

 

BD Human CD4(PE标记)抗体555347

BD Human CD4(PE标记)抗体

  • 产品型号:  555347
  • 简单描述
  • BD Human CD4(PE标记)抗体宿主物种:mouse克隆号:RPA-T4标记物:PE
详细介绍

BD Human CD4(PE标记)抗体 555347 现货供应中!

BD Human CD4(PE标记)抗体详细参数:

 

Application

Flow cytometry (Routinely Tested) 

DESCRIPTION

 

The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations. CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages. CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV). This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximay 80% of thymocytes and 45% of peripheral blood lymphocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation.

 

 

 

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development or are reported in the literature.

 

FORMAT

BD Human CD4(PE标记)抗体555347

Format

PE

Excitation Source

Blue 488 nm,Green 532 nm,Yellow/Green 561 nm

Excitation Max

496 nm

Emission Max

578 nm

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.

Other Formats →

  • APC
  • APC-Cy™7
  • APC-H7
  • APC-R700
  • Alexa Fluor® 488
  • Alexa Fluor® 647
  • Alexa Fluor® 700
  • BB515
  • BUV395
  • BV421
  • BV605
  • Biotin
  • FITC
  • NA/LE
  • PE-CF594
  • PE-Cy™5
  • PE-Cy™7
  • Pacific Blue™
  • PerCP-Cy™5.5
  • Purified

SUGGESTED COMPANION PRODUCTS

Cat No. Description Size  
555749 PE Mouse IgG1, κ Isotype Control RUO 100 Tests  

RESOURCES & TOOLS

  • Spectrum Viewer
  • Panel Designer
  • Download TDS

PREPARATION AND STORAGE

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

PRODUCT NOTICES

  1. This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-µl experimental sample (a test).
  2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
  3. Please refer to www.bdbiosciences。。com/pharmingen/protocols for technical protocols.
  4. For fluorochrome spectra and suitable instrument settings, please refer to our Multicolor Flow Cytometry web page at www.bdbiosciences。。com/colors.
  5. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
  6. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

 

BD human CD8抗体 Clone RPA-T8555366

BD human CD8抗体 Clone RPA-T8

  • 产品型号:  555366
  • 简单描述
  • BD human CD8抗体 Clone RPA-T8宿主物种:mouse反应物种:human应用:流式现货供应
详细介绍

BD human CD8抗体 Clone RPA-T8

Alternative Name:CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32

BD human CD8抗体 Clone RPA-T8

 

Reactivity

Human (QC Testing)  Rhesus, Cynomolgus, Baboon (Tested in Development) 

Application

Flow cytometry (Routinely Tested) 

Immunogen

Human CD8a

Workshop No.

IV T171; V T-CD08.03; VI 6T-CD8.1, 6T-081

Storage Buffer

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

DESCRIPTION

 

The RPA-T8 monoclonal antibody specifically binds to CD8 alpha (CD8α) . CD8α is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD8α is expressed by the majority of thymocytes, by subpopulations of αβ T cells and γδ T cells and by some NK cells. Cell surface CD8α is expressed either as a disulfide-linked homodimer (CD8αα) or as a heterodimer (CD8αβ) when disulfide-bonded to a CD8 beta chain (CD8β) . CD8-positive αβ T cells coexpress both CD8αα homodimers and CD8αβ heterodimers whereas some γδ T cells and NK cells express CD8αα homodimers. CD8 plays important roles in T cell activation and selection. The extracellular IgSF domain of CD8 α binds to a non-polymorphic determinant on HLA class I molecules (α3 domain) and enables CD8 to function as a co-receptor with MHC class I-restricted TCR during T cell recognition of antigen. The cytoplasmic domain of CD8α associates with Lck, a Src family protein tyrosine kinase that is involved in intracellular signaling. The RPA-T8 and HIT8a monoclonal antibodies are not cross-blocking. This clone has been reported to react with a subset of peripheral blood lymphocytes, but not monocytes nor granuloyctes, of baboon and both rhesus and cynomolgus macaque monkey. In general, a higher frequency of CD8+ and CD4+CD8+ lymphocytes are observed in non-human primates compared to normal human donors.

 

 

FORMAT

BD human CD8抗体 Clone RPA-T8555366

Format

FITC

Excitation Source

Blue 488 nm

Excitation Max

494 nm

Emission Max

520 nm

FITC, fluorescein isothiocyanate, is a fluorochrome with a molecular weight of 389 Da. FITC is sensitive to pH changes and photobleaching. Due to nearly identical excitation and emission properties but different spillover characteristics, FITC and Alexa Fluor® 488 cannot be used simultaneously. FITC is relatively dim and should be reserved for highly expressed markers whenever possible.

Other Formats →

  • APC
  • APC-Cy™7
  • APC-R700
  • Alexa Fluor® 488
  • Alexa Fluor® 647
  • Alexa Fluor® 700
  • BB515
  • BUV395
  • BUV496
  • BUV563
  • BV421
  • BV510
  • BV650
  • BV711
  • BV786
  • Biotin
  • NA/LE
  • PE
  • PE-CF594
  • PE-Cy™5

SUGGESTED COMPANION PRODUCTS

Cat No. Description Size  
555748 FITC Mouse IgG1, κ Isotype Control RUO 100 Tests  

RESOURCES & TOOLS

  • Spectrum Viewer
  • Panel Designer
  • Download TDS

PREPARATION AND STORAGE

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.

PRODUCT NOTICES

  1. This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-µl experimental sample (a test).
  2. An isotype control should be used at the same concentration as the antibody of interest.
  3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
  4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
  5. Species testing during development may have been performed with a different format of the same clone. Selected applications have been tested for cross-reactivity.
  6. For fluorochrome spectra and suitable instrument settings, please refer to our Multicolor Flow Cytometry web page at www.bdbiosciences。。com/colors.
  7. Please refer to www.bdbiosciences。。com/pharmingen/protocols for technical protocols.

BD human CD16 PE-CY7 MAB抗体557744

BD human CD16 PE-CY7 MAB抗体

  • 产品型号:  557744
  • 简单描述
  • BD human CD16 PE-CY7 MAB抗体宿主:mouse反应物种:human规格:100T应用:流逝
详细介绍

BD human CD16 PE-CY7 MAB抗体

英文名:PE-Cy™7 Mouse Anti-Human CD16

克隆号:Clone  3G8  (RUO)

BD human CD16 PE-CY7 MAB抗体

介绍:

 

Brand

BD Pharmingen™

Vol. Per Test

5 µl

Isotype

Mouse BALB/c x DBA/2, also known as CD2F1 or CDF1 IgG1, κ

Reactivity

Human (QC Testing)  Rhesus, Cynomolgus, Baboon (Reported) 

Application

Flow cytometry (Routinely Tested) 

Immunogen

Human polymorphonuclear leukocytes

Workshop No.

IV N409

Entrez Gene ID

2214  2215 

Storage Buffer

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Regulatory Status

RUO

 

规格

 100 Tests 25 Tests 

货号

557744

  • Product Details
  • References

DESCRIPTION

 

The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes. The 3G8 antibody is reported (Vossebeld et al., 1997) to increase intracellular calcium levels in human neutrophils by interacting with bothFcγRIIa and FcγRIIIb molecules. This antibody has also been reported to induce homotypic neutrophil aggregation.

 

 

FORMAT

BD human CD16 PE-CY7 MAB抗体557744

Format

PE-Cy™7

Excitation Source

Blue 488 nm,Green 532 nm,Yellow/Green 561 nm

Excitation Max

496 nm

Emission Max

785 nm

PE-Cy™7 is a tandem fluorochrome that combines PE and a cyanine dye. PE-Cy7 conjugated reagents are as bright as PE conjugates. PE-Cy7 is particularly sensitive to photo-induced degradation, resulting in loss of fluorescence and changes in fluorescence spillover. Extreme caution must be taken to avoid light exposure and prolonged exposure to paraformaldehyde fixative. Fixed cells should be analyzed within 4 hours of fixation in paraformaldehyde or transferred to a paraformaldehyde-free buffer for overnight storage.

Other Formats →

  • APC
  • APC-Cy™7
  • APC-H7
  • Alexa Fluor® 647
  • Alexa Fluor® 700
  • BUV395
  • BUV496
  • BUV737
  • BV421
  • BV510
  • BV605
  • BV650
  • BV711
  • BV786
  • Biotin
  • FITC
  • NA/LE
  • PE
  • PE-CF594
  • PE-Cy™5

SUGGESTED COMPANION PRODUCTS

Cat No. Description Size  
557872 PE-Cy™7 Mouse IgG1 κ Isotype Control RUO 100 Tests  

RESOURCES & TOOLS

  • Spectrum Viewer
  • Panel Designer
  • Download TDS

PREPARATION AND STORAGE

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PE-Cy7 under optimum conditions, and unconjugated antibody and free PE-Cy7 were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

 

DAKO CD20抗体(Mouse Anti-Human CD20cy)M0755

DAKO CD20抗体(Mouse Anti-Human CD20cy)

  • 产品型号:  M0755
  • 简单描述
  • DAKO CD20抗体(Mouse Anti-Human CD20cy)规格:0.2ml单克隆小鼠抗人CD20cy抗体*!
详细介绍

DAKO CD20抗体(Mouse Anti-Human CD20cy)

克隆号:L26

该抗体可与一种非常有用的正常和肿瘤性B细胞的非常有用标记的抗原反应。该抗体能与位于CD20抗原上的一种胞质内表位反应,该抗体可与DAKO抗CD3多克隆抗体相配合用于鉴别T细胞和B细胞。该抗体有有助于鉴别霍奇金淋巴瘤中的霍奇金细胞和Read-sternberg细胞

DAKO CD20抗体(Mouse Anti-Human CD20cy)

 

现货供应*!

DAKO鼠抗人CD56抗体(Human CD56 Clone 123C3)M7304

DAKO鼠抗人CD56抗体(Human CD56 Clone 123C3)

  • 产品型号:  M7304
  • 简单描述
  • DAKO鼠抗人CD56抗体(Human CD56 Clone 123C3)规格:0.2ml英文名:Monoclonal Mouse Anti-Human CD56 Clone123C3现货*1
详细介绍

DAKO鼠抗人CD56抗体(Human CD56 Clone 123C3)

英文名:Monoclonal Mouse Anti-Human CD56 Clone123C3

克隆号:123C3

类型:冰冻切片,石蜡切片,热修复

DAKO鼠抗人CD56抗体(Human CD56 Clone 123C3)

该抗体可与自然杀伤细胞及外周血中的一部分CD4+和CD8+T细胞反应,除了造血系统外,CD56也在包括神经母细胞和小细胞肺癌(SCLC)等多重肿瘤中表达

 

详细产品产品可和选购!

 

DAKO鼠抗人CD8抗体anti-human CD8 clone C8/144BIR623

DAKO鼠抗人CD8抗体anti-human CD8 clone C8/144B

  • 产品型号:  IR623
  • 简单描述
  • DAKO鼠抗人CD8抗体anti-human CD8 clone C8/144B英文名:Monoclonal Mouse Anti-Human antibody
详细介绍

DAKO鼠抗人CD8抗体anti-human CD8 clone C8/144B

CD8 is a 68 kDa transmembrane glycoprotein expressed as a heterodimer by a majority of thymocytes, and by class I major histocompatibility complex restricted, mature, suppressor/cytotoxic T cells.

The antibody is a useful aid for classification of cytotoxic/suppressor T-cell lymphomas.

 

详细产品信息和和选购!

DAKO Monoclonal Mouse Anti-Human CD45R0抗体M0742

DAKO Monoclonal Mouse Anti-Human CD45R0抗体

  • 产品型号:  M0742
  • 简单描述
  • DAKO Monoclonal Mouse Anti-Human CD45R0抗体Clone UCHL1规格:1ml
详细介绍

DAKO Monoclonal Mouse Anti-Human CD45R0抗体

CD45 is a transmembrane glycoprotein expressed on most nucleated cells of hematopoetic origin. On human leucocytes, five different isoforms of CD45 have been identified, named ABC, AB, BC, B and 0. This antibody reacts with an epitope unique for CD45R0. The antibody labels most thymocytes, a subpopulation of resting T cells within both CD4 and CD8 subsets, and mature, activated T cells. It is effective on formalin-fixed, paraffin-embedded tissue sections. Results aid in the classification of T-cell neoplasms.

DAKO Monoclonal Mouse Anti-Human CD45R0抗体

我公司代理DAKO产品,详细产品信息可和选购!

DAKO抗体是丹麦的著名抗体生产商,提供世界上质量zui稳定,zui为经典的抗体。其主要产品涉及免疫化学、流式细胞,免疫组织化学,原位杂交,微生物检验等。DAKO的不同显色系统,Envision,LSAB和免疫细胞化学的CAS,GenpointTM和用于分子病理学的PNA=ISH试剂盒,和用于ELISA的AMPAKTM/AmpliQ是其在生物化学研究中的革新产品 。

 

 

DAKO Rabbit Anti-Human IgG A0423A0423

DAKO Rabbit Anti-Human IgG A0423

  • 产品型号:  A0423
  • 简单描述
  • DAKO Rabbit Anti-Human IgG A0423规格:1ml现货*
详细介绍

DAKO Rabbit Anti-Human IgG A0423

DAKO抗体是丹麦的著名抗体生产商,提供世界上质量zui稳定,zui为经典的抗体。其主要产品涉及免疫化学、流式细胞,免疫组织化学,原位杂交,微生物检验等。DAKO的不同显色系统,Envision,LSAB和免疫细胞化学的CAS,GenpointTM和用于分子病理学的PNA=ISH试剂盒,和用于ELISA的AMPAKTM/AmpliQ是其在生物化学研究中的革新产品 。

DAKO Rabbit Anti-Human IgG A0423

详细产品信息可和选购,我公司备有大量dako(丹科)公司现货产品!

DAKO(丹科)anti-human CD31抗体 Clone JC70AM0823

DAKO(丹科)anti-human CD31抗体 Clone JC70A

  • 产品型号:  M0823
  • 简单描述
  • DAKO(丹科)anti-human CD31抗体 Clone JC70Acompany name : Dakoproduct type : antibodyproduct name : CD31, Endothelial Cellcatalog : M0823
详细介绍

DAKO(丹科)anti-human CD31抗体 Clone JC70A

clonality :

monoclonal

host :

mouse

reactivity :

human

publications citing this reagent :

  1. human (IHC)

    Dimitrijevic I, Edvinsson M, Chen Q, Malmsjo M, Kimblad P, Edvinsson L. Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. BMC Cardiovasc Disord. 2009;9:40 pubmed publisher

  2. Hendrickson A, Troilo D, Djajadi H, Possin D, Springer A. Expression of synaptic and phototransduction markers during photoreceptor development in the marmoset monkey Callithrix jacchus. J Comp Neurol. 2009;512:218-31 pubmed publisher

  3. Hendrickson A, Troilo D, Possin D, Springer A. Development of the neural retina and its vasculature in the marmoset Callithrix jacchus. J Comp Neurol. 2006;497:270-86 pubmed

more info or order :

Dako product webpage

product information

Clone Number :

JC70A

Host :

mouse

Product Name :

CD31, Endothelial Cell

Code :

M0823

reactive species :

human

more info or order :

Dako product webpage

DAKO(丹科)anti-human CD31抗体 Clone JC70A
详细产品信息可和选购