组成品

状态

包装

KLH包被96孔板

清洗后使用

96 wells（8×12）／1个

抗KLH大鼠IgM标准溶液（1000ng/mL）

稀释后使用

200μL/1瓶

缓冲液

直接使用

100mL/1瓶

HRP结合抗大鼠IgM抗体

稀释后使用

100μL/1瓶

显色液（TMB）

直接使用

12mL/1瓶

终止液（1M H₂SO₄）※小心轻放

直接使用

12mL/1瓶

浓缩清洗液（10×）

稀释后使用

100mL/1瓶

孔板密封膜

3个

产品说明书

1本

动物种类

对象物质

反应性及反应率（%）

大鼠

IgM

100

IgG

―

IgA

―

IgE

―

小鼠

IgG

―

IgM

―

IgE

―

样本

A

B

1

49.5

164

2

47.7

166

3

48.0

164

4

47.6

161

5

49.7

169

Mean

48.5

165

SD

1.03

2.93

CV（%）

2.1

1.8

测定日/样本

E

F

G

0天

11.1

86.5

187

1天

11.1

86.1

188

2天

11.2

86.3

188

3天

11.1

83.3

186

Mean

11.1

85.6

187

SD

0.0576

1.48

0.814

CV（%）

0.52

1.7

0.44

添加量

实测值

回收量

回收率（%）

0.00

47.3

—

—

102

144

96.7

94.8

127

172

125

98.4

140

182

135

96.4

添加量

实测值

回收量

回收率（%）

0.00

34.8

—

—

16.8

51.9

17.1

102

25.2

59.5

24.7

98.0

42.0

76.7

41.9

99.8

产品编号

产品名称

包装

所含成分

134-16201

Multielement Standard Solution W-X

多元混合阳离子标准溶液W-X

50 mL

Cd, Cr, Se, Pd, As, Zn, Al, Cu, Mn 

131-16211

Multielement Standard Solution W-XI 

多元混合阳离子标准溶液W-XI

50 mL

Co, Ga, In, Tl, Y, Be

产品编号

产品名

规格

包装

138-11461

Multielement Standard Solution L-I (for ICP Analysis)
  多元素标准溶液L-1
Al:1,000 Ba:100 Ca:1,000 Cr:100 Fe:1,000 Mg:100 Pb:100 Sr:100 (mg/L in 1 mol/L·HNO₃

50 mL

135-11471

Multielement Standard Solution L-II (for ICP Analysis)
多元素标准溶液L-II
Cu:100 Mn:100 Ni:100 V:100 Zn:100 (mg/L in 1 mol/L·H₂SO₄)

50 mL

137-11431

Multielement Standard Solution R-I (for ICP Analysis)
多元素标准溶液R-I
Ce:100 La:100 Pr:100 Sc:100 Y:100 (mg/L in 1 mol/L·HNO₃)

50 mL

134-11441

Multielement Standard Solution R-II (for ICP Analysis)
多元素标准溶液R-II
Eu:100 Gd:100 Nd:100 Sm:100 Tb:100 (mg/L in 1 mol/L·HNO₃)

 50 mL

131-11451

Multielement Standard Solution R-III (for ICP Analysis)
多元素标准溶液R-III
Dy:100 Er:100 Ho:100 Tm:100 Yb:100 (mg/L in 1 mol/L·HNO₃)

50 mL

139-11491

Multielement Standard Solution W-I (for ICP Analysis)
多元混合标准溶液W-I
K:2,000 Na:2,000 P:1,000 (mg/L in 1 mol/L·H₂O)

50 mL

132-11501

Multielement Standard Solution W-II (for ICP Analysis)
多元混合标准溶液W-II
Ca:1,000 Co:100 Fe:100 Mg:1,000 Mn:100 Ni:100 (mg/L in 1 mol/L·HNO₃)

50 mL

139-11511

Multielement Standard Solution W-III (for ICP Analysis)
多元混合标准溶液W-III
Cd:100 Cr:100 Cu:1,000 Pb:100 Zn:1,000 (mg/L in 1 mol/L·HNO₃)

50 mL

139-11871

Multielement Standard Solution W-IV (for ICP Analysis)
多元素标准溶液W-IV
Cd:100 Cr:100 Cu:100 Fe:100 Mn:100 Na:100 Pb:100 Zn:100 (mg/L in 0.1 mol/L · HNO₃)

50 mL

138-13781

Multielement Standard Solution W-V (for ICP Analysis)
多元混合标准溶液W-V
Al:100 B:100 Cd:100 Cr:100 Cu:100 Fe:100 Mn:100 Mo:100 Na:100 Ni:100 Pb:100 Zn:100 (mg/L in 1 mol/L·HNO₃)

50 mL

139-14551

Multielement Standard Solution W-VI (for ICP Analysis)
多元混合标准溶液 W-VI
Al:100 B:100 Cd:100 Cr:100 Cu:100 Fe:100 Mn:100   Mo:100 Na:100 Ni:100 Pb:100 Zn:100 (mg/L in 0.1 mol/L·HNO₃)

50 mL

组分

量

组分

量

NaNO3

200

CoSO4·7H2O

0.014

Na2HPO4

1

Na2MoO4·2H2O

0.0073

K2HPO4

5

CuSO4·5H2O

0.0025

NH4Cl

2.68

H2SeO3

0.0017

Fe-EDTA

5.2

Thiamin-HCl

0.2

Mn-EDTA

0.332

Biotin

0.0015

NA2-EDTA

37.2

Vitamin B12

0.0015

ZnSO4·7H2O

0.023

MnCl2·4H2O

0.18

组分

量

组分

量

MgCl2·6H2O

9,474

LiCl

1

CaCl2·2H2O

1,326

Kl

0.07

Na2SO4

3,505

CoCl2·6H2O

0.0002

KCl

597

AlCl3·6H2O

0.008

NaHCO3

171

FeCl3·6H2O

0.005

KBr

85

Na2WO4·2H2O

0.0002

Na2B4O7·10H2O

34

(NH4)6Mo7O24·4H2O

0.02

SrCl2

12

MnCl2·4H2O

0.0008

NaF

3

NaCl

20,747

植物研究用试剂

组成

状态

容量

(A) 抗体固相化 96 孔板

洗净后使用

96   wells（8×12）／1 块

(B) 胰岛素标准溶液（大鼠）（200 ng/mL）

稀释后使用

25 μL／1 瓶

(C) 缓冲液

即用

60 mＬ／1 瓶

(D) 生物素结合抗胰岛素抗体

稀释后使用

10 μＬ／1 瓶

(E) 过氧化物・抗生物素蛋白结合物

稀释后使用

20 μＬ／1 瓶

(F) 显色液（TMB）

即用

12 mL／1 瓶

(H) 反应终止液（1M H2SO4）※小心轻放

即用

12 mL／1 瓶

( I ) 浓缩洗净液（10×）

稀释后使用

100 mL／1 瓶

封板膜

3 张

使用说明书

1 份

样品

A

B

C

D

1

0.589

1.211

2.600

4.991

2

0.568

1.228

2.600

4.971

3

0.568

1.228

2.532

5.036

4

0.557

1.211

2.538

5.026

5

0.557

1.253

2.582

4.925

6

0.578

1.220

2.563

4.880

7

0.578

1.228

2.618

5.031

8

0.536

1.228

2.618

4.885

mean

0.566

1.226

2.581

4.968

SD

0.0165

0.0131

0.0340

0.0645

CV(%)

2.92

1.07

1.32

1.30

测量日/样品

E

F

G

第0天

6.74

3.31

1.16

第1天

6.69

3.25

1.22

第2天

6.23

3.21

1.21

mean

6.55

3.25

1.20

SD

0.2792

0.0479

0.0325

CV(%)

4.3

1.5

2.7

添加量

理论值

实测值

回收率(%)

0

–

0.996

–

0.500

1.496

1.484

99.2

1.000

1.996

2.048

103

2.000

2.996

2.779

92.7

添加量

理论值

实测值

回收率(%)

0

–

1.086

–

0.500

1.586

1.562

98.5

1.000

2.086

2.061

98.8

2.000

3.086

2.753

89.2

添加量

理论值

实测值

回收率(%)

0

–

1.160

–

0.500

1.660

1.637

98.6

1.000

2.160

2.054

95.1

2.000

3.166

2.963

93.6

ELISA试剂盒选择指南①②

 1.

Canagliflozin potentiates GLP-1 secretion and lowers the peak of GIP secretion in rats fed a high-fat high-sucrose diet. Hira T, Koga T, Sasaki K, Hara H. Biochem Biophys Res Commun. 2017 Oct 14;492(2):161-165.

 2.

Imidacloprid insecticide exposure induces stress and disrupts glucose homeostasis in male rats. Khalil SR, Awad A, Mohammed HH, Nassan MA. Environ Toxicol Pharmacol. 2017 Oct;55:165-174.

 3.

Effects of short-term fasting on the Akt-mediated pathway involved in protein metabolism in chicken skeletal muscle. Saneyasu T, Tsuchii N, Nakano Y, Kitashiro A, Tsuchihashi T, Shindo H, Honda K, Kamisoyama H. Domest Anim Endocrinol. 2017 Oct;61:54-61.

 4.

Impact of difructose anhydride III, raffinose, and fructooligosaccharides on energy intake, gut hormones, and cecal fermentation in rats fed a high-fat and high-sucrose diet. Hira T, Yanagihara K, Koga T, Takahashi K, Nagura T, Uchino H, Hara H. Biosci Biotechnol Biochem. 2017 Sep 27:1-9.

 5.

Branched-chain amino acid supplementation restores reduced insulinotropic activity of a low-protein diet through the vagus nerve in rats. Horiuchi M, Takeda T, Takanashi H, Ozaki-Masuzawa Y, Taguchi Y, Toyoshima Y, Otani L, Kato H, Sone-Yonezawa M, Hakuno F, Takahashi SI, Takenaka A. Nutr Metab (Lond). 2017 Sep 15;14:59.

 6.

Role of Glyceraldehyde-derived AGEs and Mitochondria in Superoxide Production in Femoral Artery of OLETF Rat and Effects of Pravastatin. Hori E, Kikuchi C, Nagami C, Kajikuri J, Itoh T, Takeuchi M, Matsunaga T. Biol Pharm Bull. 2017 Aug 22.

 7.

Glucagon-like peptide-1 reduces pancreatic β-cell mass through hypothalamic neural pathways in high-fat diet-induced obese rats. Ando H, Gotoh K, Fujiwara K, Anai M, Chiba S, Masaki T, Kakuma T, Shibata H. Sci Rep. 2017 Jul 17;7(1):5578.

 8.

Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease. Kugita M, Nishii K, Yamaguchi T, Suzuki A, Yuzawa Y, Horie S, Higashihara E, Nagao S PLoS One. 2017 May 18;12(5):e0177934.

 9.

Green tea extract intake during lactation modified cardiac macrophage infiltration and AMP-activated protein kinase phosphorylation in weanling rats from undernourished mother during gestation and lactation. Matsumoto E, Kataoka S, Mukai Y, Sato M, Sato S. J Dev Orig Health Dis. 2017 Apr;8(2):178-187.

10.

Exogenous thyroxine improves glucose intolerance in insulin-resistant rats. Vazquez-Anaya G, Martinez B, Sonanez-Organis JG, Nakano D, Nishiyama A, Ortiz RM. J Endocrinol. 2017 Mar;232(3):501-511.

11.

Beneficial effects of metformin on energy metabolism and visceral fat volume through a possible mechanism of fatty acid oxidation in human subjects and rats. Tokubuchi I, Tajiri Y, Iwata S, Hara K, Wada N, Hashinaga T, Nakayama H, Mifune H, Yamada K PLoS One. 2017 Feb 3;12(2):e0171293.

12.

Resistant maltodextrin or fructooligosaccharides promotes GLP-1 production in male rats fed a high-fat and high-sucrose diet, and partially reduces energy intake and adiposity. Hira T, Suto R, Kishimoto Y, Kanahori S, Hara H. Eur J Nutr. 2017 Feb 4.

13.

Lactoferrin ameliorates corticosterone-related acute stress and hyperglycemia in rats. Maekawa Y. Sugiyama A, Takeuchi T. J Vet Med Sci. 2017 Feb 28;79(2):412-417.

14.

Dioscorea esculenta-induced increase in muscle sex steroid hormones is associated with enhanced insulin sensitivity in a type 2 diabetes rat model. Sato K, Fujita S, Iemitsu M. FASEB J. 2017 Feb;31(2):793-801.

15.

Mild Hyperbaric Oxygen Inhibits Growth-related Decrease in Muscle Oxidative Capacity of Rats with Metabolic Syndrome. Takemura A, Ishihara A. J Atheroscler Thromb. 2017 Jan 1;24(1):26-38.

16.

The Sodium Glucose Cotransporter 2 Inhibitor Ipragliflozin Promotes Preferential Loss of Fat Mass in Non-obese Diabetic Goto?Kakizaki Rats. Toshiyuki Takasu,  Yuka Hayashizaki,  Jiro Hirosumi,  Hideaki Minoura,  Nobuaki Amino,  Eiji Kurosaki,  Shoji Takakura. Biological and Pharmaceutical Bulletin, Vol.40 (2017), No. 5, p.675-680

17.

Anti-Prediabetic Effect of 6-O-Caffeoylsophorose in Prediabetic Rats and Its Stimulation of Glucose Uptake in L6 Myotubes. Gonzalo Miyagusuku-Cruzado,  Naoki Morishita,  Keiichi Fukui,  Norihiko Terahara,  Toshiro Matsui. Food Science and Technology Research, Vol.23(2017),  No.3, p.449-456

18.

The Sodium Glucose Cotransporter 2 Inhibitor Ipragliflozin Promotes Preferential Loss of Fat Mass in Non-obese Diabetic Goto-Kakizaki Rats. Takasu T, Hayashizaki Y, Hirosumi J, Minoura H, Amino N, Kurosaki E, Takakura S. Biol Pharm Bull. 2017;40(5):675-680.

19.

Evaluation of the Effects and Mechanism of L-Citrulline on Anti-obesity by Appetite Suppression in Obese/Diabetic KK-Ay Mice and High-Fat Diet Fed SD Rats. Kudo M, Yoshitomi H, Momoo M, Suguro S, Yamagishi Y, Gao M. Biol Pharm Bull. 2017;40(4):524-530.

20.

Exogenous thyroxine improves glucose intolerance in insulin-resistant rats. Vazquez-Anaya G, Martinez B, Sonanez-Organis JG, Nakano D, Nishiyama A, Ortiz RM. J Endocrinol. 2017 Mar;232(3):501-511

21.

Anti-prediabetic effect of rose hip (Rosa canina) extract in spontaneously diabetic Torii rats. Chen SJ, Aikawa C, Yoshida R, Kawaguchi T, Matsui T. J Sci Food Agric. 2017 Feb 9.

22.

O leuropein aglycone enhances UCP1 expression in brown adipose tissue in high-fat-diet-induced obese rats by activating β-adrenergic signaling. Oi-Kano Y, Iwasaki Y, Nakamura T, Watanabe T, Goto T, Kawada T, Watanabe K, Iwai K. J Nutr Biochem. 2017 Feb;40:209-218.

23.

Beneficial effects of metformin on energy metabolism and visceral fat volume through a possible mechanism of fatty acid oxidation in human subjects and rats. Tokubuchi I, Tajiri Y, Iwata S, Hara K, Wada N, Hashinaga T, Nakayama H, Mifune H, Yamada K. PLoS One. 2017 Feb 3;12(2):e0171293

24.

Resistant maltodextrin or fructooligosaccharides promotes GLP-1 production in male rats fed a high-fat and high-sucrose diet, and partially reduces energy intake and adiposity. Hira T, Suto R, Kishimoto Y, Kanahori S, Hara H. Eur J Nutr. 2017 Feb 4.

25.

Lactoferrin potentially facilitates glucose regulation and enhances the incretin effect. Maekawa Y， Sugiyama A, Takeuchi T. Biochem Cell Biol. 2017 Feb;95(1):155-161.

26.

Mild Hyperbaric Oxygen Inhibits Growth-related Decrease in Muscle Oxidative Capacity of Rats with Metabolic Syndrome. Takemura A, Ishihara A. J Atheroscler Thromb. 2017 Jan 1;24(1):26-38.

27.

Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high-phosphate-induced mitochondrial oxidative stress and defective insulin secretion. Nguyen TT, Quan X, Xu S, Das R, Cha SK, Kong ID, Shong M, Wollheim CB, Park KS. FASEB J. 2016 Dec;30(12):3979-3988

28.

Plekhs1 and Prdx3 are candidate genes responsible for mild hyperglycemia associated with obesity in a new animal model of F344-fa-nidd6 rat. Kotoh J, Sasaki D, Matsumoto K, Maeda A. J Vet Med Sci. 2016 Dec 1;78(11):1683-1691.

29.

Melinjo (Gnetum gnemon) extract intake during lactation stimulates hepatic AMP-activated protein kinase in offspring of excessive fructose-fed pregnant rats. Kataoka S, Mukai Y, Takebayashi M, Kudo M, Acuram UR, Kurasaki M, Sato S. Reprod Biol. 2016 Jun;16(2):165-73

30.

Rice (Oryza sativa japonica) Albumin Suppresses the Elevation of Blood Glucose and Plasma Insulin Levels after Oral Glucose Loading. Ina S, Ninomiya K, Mogi T, Hase A, Ando T, Matsukaze N, Ogihara J, Akao M, Kumagai H, Kumagai H. J Agric Food Chem. 2016 Jun 22;64(24):4882-90.

31.

PPARγ activation alters fatty acid composition in adipose triglyceride, in addition to proliferation of small adipocytes, in insulin resistant high-fat fed rats. Sato D, Oda K, Kusunoki M, Nishina A, Takahashi K, Feng Z, Tsutsumi K, Nakamura T. Eur J Pharmacol. 2016 Feb 15;773:71-7.

32.

Exercise and dietary change ameliorate high fat diet induced obesity and insulin resistance via mTOR signaling pathway. Bae JY, Shin KO, Woo J, Woo SH, Jang KS, Lee YH, Kang S. J Exerc Nutrition Biochem. 2016 Jun;20(2):28-33.

33.

The IGF-1/Akt/S6 Signaling Pathway is Age-Dependently Downregulated in the Chicken Breast Muscle. Takaoki Saneyasu, Mariko Inui, Sayaka Kimura, Yu Yoshimoto, Nami Tsuchii, Haruka Shindo, Kazuhisa Honda, Hiroshi Kamisoyama. The Journal of Poultry Science, Article ID: 0150171

34.

The dipeptidyl peptidase IV inhibitor vildagliptin suppresses development of neuropathy in diabetic rodents: Effects on peripheral sensory nerve function, structure and molecular changes. Tsuboi K, Mizukami H, Inaba W, Baba M, Yagihashi S. J Neurochem. Vol.136, Issue 4, Feb. 2016, p859–870

35.

Characterization of bioactive agents in five types of marketed sprouts and comparison of their antihypertensive, antihyperlipidemic, and antidiabetic effects in fructose-loaded SHRs. Nakamura K, Koyama M, Ishida R, Kitahara T, Nakajima T, Aoyama T. J Food Sci Technol. 2016 Jan;53(1):581-90.

36.

Beneficial effect of D-allose for isolated islet culture prior to islet transplantation. Kashiwagi H, Asano E, Noguchi C, Sui L, Hossain A, Akamoto S, Okano K, Tokuda M, Suzuki Y. J Hepatobiliary Pancreat Sci. 2016 Jan;23(1):37-42.

37.

Characterization of bioactive agents in five types of marketed sprouts and comparison of their antihypertensive, antihyperlipidemic, and antidiabetic effects in fructose-loaded SHRs. Nakamura K, Koyama M, Ishida R, Kitahara T, Nakajima T, Aoyama T. J Food Sci Technol. 2016 Jan;53(1):581-90.

38.

Characterization of the Prediabetic State in a Novel Rat Model of Type 2 Diabetes, the ZFDM Rat. Gheni G, Yokoi N, Beppu M, Yamaguchi T, Hidaka S, Kawabata A, Hoshino Y, Hoshino M, Seino S. J Diabetes Res. 2015:261418.

39.

The dipeptidyl peptidase IV inhibitor vildagliptin suppresses development of neuropathy in diabetic rodents: Effects on peripheral sensory nerve function, structure and molecular changes. Tsuboi K, Mizukami H, Inaba W, Baba M, Yagihashi S. J Neurochem. 2015 Nov 25.

40.

Resistant maltodextrin promotes fasting glucagon-like peptide-1 secretion and production together with glucose tolerance in rats. Hira T, Ikee A, Kishimoto Y, Kanahori S, Hara H. Br J Nutr. Vol.114(1), p34-42, Jul 2015.

41.

Rice protein hydrolysates stimulate GLP-1 secretion, reduce GLP-1 degradation, and lower the glycemic response in rats. Ishikawa Y, Hira T, Inoue D, Harada Y, Hashimoto H, Fujii M, Kadowaki M, Hara H. Food Funct. Jun 2015.

42.

L-Citrulline increases hepatic sensitivity to insulin by reducing the phosphorylation of serine 1101 in insulin receptor substrate-1. Yoshitomi H, Momoo M, Ma X, Huang Y, Suguro S, Yamagishi Y, Gao M. BMC Complement Altern Med. Vol.15:188, Jun 2015.

43.

Black soybean extract reduces fatty acid contents in subcutaneous, but not in visceral adipose triglyceride in high-fat fed rats Sato D, Kusunoki M, Seino N, Nishina A, Feng Z, Tsutsumi K, Nakamura T. International Journal of Food Sciences and Nutrition , Published online: 20 May 2015.

44.

Fasting for 3 days during the suckling-weaning transient period in male rats induces metabolic abnormalities in the liver and is associated with impaired glucose tolerance in adulthood. Ikeda M, Honma K, Mochizuki K, Goda T. Eur J Nutr. May 2015.

45.

Stimulatory effect of insulin on renal proximal tubule sodium transport is preserved in type 2 diabetes with nephropathy. Nakamura M, Satoh N, Suzuki M, Kume H, Homma Y, Seki G, Horita S. Biochem Biophys Res Commun. Vol.461(1), p154-8, May 2015.

46.

Preserved Na/HCO3 cotransporter sensitivity to insulin may promote hypertension in metabolic syndrome. Nakamura M, Yamazaki O, Shirai A, Horita S, Satoh N, Suzuki M, Hamasaki Y, Noiri E, Kume H, Enomoto Y, Homma Y, Seki G. Kidney Int. Vol.87(3), p535-42, Mar 2015.

47.

Dietary protein derived from dried bonito fish improves type-2 diabetes mellitus-induced bone frailty in Goto-Kakizaki rats. Ochiai M, Kuroda T, Gohtani S, Matsuo T. J Food Sci. Vol.80(4), p848-56, Apr 2015.

48.

Ability of natural astaxanthin from shrimp by-products to attenuate liver oxidative stress in diabetic rats. Sila A, Kamoun Z, Ghlissi Z, Makni M, Nasri M, Sahnoun Z, Nedjar-Arroume N, Bougatef A. Pharmacol Rep. Vol.67(2), p310-6. Apr 2015.

49.

The effects of black garlic (Allium satvium) extracts on lipid metabolism in rats fed a high fat diet. Ha AW, Ying T, Kim WK. Nutr Res Pract. 2015 Feb;9(1):30-6.

50.

Resistant maltodextrin promotes fasting glucagon-like peptide-1 secretion and production together with glucose tolerance in rats. Hira T, Ikee A, Kishimoto Y, Kanahori S, Hara H. Br J Nutr. Vol.11:1-9. Feb 2015.

51.

 Effects of sleeve gastrectomy and gastric banding on the hypothalamic feeding center in an obese rat model. Kawasaki T, Ohta M, Kawano Y, Masuda T, Gotoh K, Inomata M, Kitano S. Surg Today. Feb 2015.

52.

Preventive effects of the angiotensin-converting enzyme inhibitor, captopril, on the development of azoxymethane-induced colonic preneoplastic lesions in diabetic and hypertensive rats. Kochi T, Shimizu M, Ohno T, Baba A, Sumi T, Kubota M, Shirakami Y, Tsurumi H, Tanaka T, Moriwaki H. Oncol Lett. Vol.8(1), p223-229. Jul 2014.

53.

Dietary Protein Derived from Dried Bonito Fish Improves Type-2 Diabetes Mellitus-Induced Bone Frailty in Goto-Kakizaki Rats. Ochiai M1, Kuroda T, Gohtani S, Matsuo T. J Food Sci. Feb 2015.

54.

Pancreatic fat accumulation, fibrosis, and acinar cell injury in the Zucker diabetic fatty rat fed a chronic high-fat diet. Matsuda A, Makino N, Tozawa T, Shirahata N, Honda T, Ikeda Y, Sato H, Ito M, Kakizaki Y, Akamatsu M, Ueno Y, Kawata S. Pancreas. Vol.43(5), p735-743. Jul 2014.

55.

Comparison of mechanisms underlying changes in glucose utilization in fasted rats anesthetized with propofol or sevoflurane: Hyperinsulinemia is exaggerated by propofol with concomitant insulin resistance induced by an acute lipid load. Li X, Kitamura T, Kawamura G, Mori Y, Sato K, Araki Y, Sato R, Yamada Y. Biosci Trends.Vol.8(3), p155-162. Jun 2014.

56.

Chronic Administration of Bovine Milk-Derived α-Lactalbumin Improves Glucose Tolerance via Enhancement of Adiponectin in Goto-Kakizaki Rats with Type 2 Diabetes. Yamaguchi M., Takai S. Biological and Pharmaceutical Bulletin, Vol. 37 (2014) No. 3, p.404-408, 2014.

57.

Maternal fructose intake during pregnancy modulates hepatic and hypothalamic AMP-activated protein kinase signaling in gender-specific manner in offspring. Mukai Y., Ozaki H., Serita Y. and Sato S. Clinical and Experimental Pharmacology and Physiology, 2014.

58.

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Glucose Use in Fasted Rats Under Sevoflurane Anesthesia and Propofol Anesthesia. K.Sato, T.Kitamura, G.Kawamura, Y.Mori, R.Sato, Y.Araki, Y.Yamada. Anesth Analg, Jun 2013.

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Oral administration of corn Zein hydrolysate stimulates GLP-1 and GIP secretion and improves glucose tolerance in male normal rats and Goto-Kakizaki rats. N.Higuchi, T.Hira, N.Yamada and H.Hara. Endocrinology, Jun 2013.

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Pancreatic stellate cells reduce insulin expression and induce apoptosis in pancreatic β-cells. Kikuta K, Masamune A, Hamada S, Takikawa T, Nakano E, Shimosegawa T. Biochemical and Biophysical Research Communications,Available online 13, Mar 2013

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Hypothalamic Brain-Derived Neurotrophic Factor Regulates Glucagon Secretion Mediated by Pancreatic Efferent Nerves. Gotoh K, Masaki T, Chiba S, Ando H, Fujiwara K, Shimasaki T, Mitsutomi K, Katsuragi I, Kakuma T, Sakata T, Yoshimatsu H. Journal of Neuroendocrinology, Vol.25(3), p302-311, Mar 2013.

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Effects of electrical microstimulation of peripheral sympathetic nervous fascicle on glucose uptake in rats. Sato D, Shinzawa G, Kusunoki M, Matsui T, Sasaki H, Feng Z, Nishina A, Nakamura T. Journal of Artificial Organs, Mar 2013.

73.

Improvement of erectile function by Korean red ginseng (Panax ginseng) in a male rat model of metabolic syndrome. Kim S-D, Kim Y-J, Huh J-S, Kim S-W and Sohn D-W. Asian Journal of Andrology , Feb 2013.

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Quercetin intake during lactation modulates the AMP-activated protein kinase pathway in the livers of adult male rat offspring programmed by maternal protein restriction. Sato S., Mukai Y., Saito T. The Journal of Nutritional Biochemistry, Vol.24(1), p118-123, Jan 2013.

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Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction. Sasaki M, Fujimoto S, Sato Y, Nishi Y, Mukai E, Yamano G, Sato H, Tahara Y, Ogura K, Nagashima K and Inagaki N. Diabetes, January 24, 2013 , In press.

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Derangement of ghrelin secretion after long-term high-fat diet feeding in rats. Sugiishi A, Kimura M, Kamiya R, Ueki S, Yoneya M, Saito Y, Saito H. Hepatology Research, 2013, In press.

77.

Proteomic and bioinformatic analysis of membrane proteome in type 2 diabetic mouse liver. Kim G-H, Park E C, Yun S-H, Hong Y, Lee D-G, Shin E-Y, Jung J, Kim Y H, Lee K-B, Jang I-S, Lee Z-W, Chung Y-H, Choi J-S, Cheong C, Kim S, Kim S II. PROTEOMICS, 2013, In press.

78.

A Novel Rat Model of Type 2 Diabetes: The Zucker Fatty Diabetes Mellitus ZFDM Rat. Yokoi N, Hoshino M, Hidaka S, Yoshida E, Beppu M, Hoshikawa R, Sudo K, Kawada A, Takagi S and Seino S. Journal of Diabetes Research, Vol.2013 (2013)

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Urinary cystatin C as a biomarker for diabetic nephropathy and its immunohistochemical localization in kidney in Zucker diabetic fatty (ZDF) rats. Togashi Y, Miyamoto Y. Experimental and Toxicologic Pathology,Available online 12 Jul 2012.

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Artemisia campestris leaf extract alleviates early diabetic nephropathy in rats by inhibiting protein oxidation and nitric oxide end products. Mediha S, Hamadi F, Nejla S, Yassine C, Mohamed M, Najiba Z. Pathology – Research and Practice, Vol.208(3), p157-162, Mar 2012.

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Fenugreek with reduced bitterness prevents diet-induced metabolic disorders in rats. Muraki E, Chiba H, Taketani K, Hoshino S, Tsuge N, Tsunoda N and Kasono K. Lipids in Health and Disease, Vol.11(58), 2012.

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Oral Ingestion of Aloe vera Phytosterols Alters Hepatic Gene Expression Profiles and Ameliorates Obesity-Associated Metabolic Disorders in Zucker Diabetic Fatty Rats. E. Misawa., M. Tanaka., K. Nomaguchi., K. Nabeshima., M. Yamada., T. Toida., and K. Iwatsuki. J. Agric. Food Chem., 2012, 60 (11), pp 2799-2806

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 Myocardial Infarction-Prone Watanabe Heritable Hyperlipidemic Rabbits with Mesenteric Fat Accumulation Are a Novel Animal Model for Metabolic Syndrome. M. Shiomi., T. Kobayashi., N. Kuniyoshi., S. Yamada., T. Ito. Pathobiology 2012;Vol. 79 No. 6 P329-338

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High-fat diet-induced reduction of peroxisome proliferator-activated receptor-γ coactivator-1α messenger RNA levels and oxidative capacity in the soleus muscle of rats with metabolic syndrome. F. Nagatomo., H. Fujino., H. Kondo., I. Takeda., K. Tsuda., A. Ishihara. Nutrition Research, Vol. 32, Issue 2, February 2012, Pages 144-151

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The effects of running exercise on oxidative capacity and PGC-1α mRNA levels in the soleus muscle of rats with metabolic syndrome. F. Nagatomo., H. Fujino., H. Kondo., M. Kouzaki., N. Gu., I. Takeda., K. Tsuda., and A. Ishihara. The Journal of Physiological Sciences, Vol. 62, Number 2 (2012), 105-114

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A Comparative Study of Gastric Banding and Sleeve Gastrectomy in an Obese Diabetic Rat Model. T. Masuda., M. Ohta., T. Hirashita., Y. Kawano., H. Egucji., K. Yada., Y. Iwashita., S. Kitano. Obesity Surgery, Published online:27 August 2011

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Site dependency of fatty acid composition in adipose triacylglycerol in rats and its absence as a result of high-fat feeding. D. Sato., T. Nakamura., K. Tsutsumi., G. Shinzawa., T. Karimata., T. Okawa., Z. Fengc., and M. Kusunoki. Metabolism.Article in Press

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Dietary fructo-oligosaccharides improve insulin sensitivity along with the suppression of adipocytokine secretion from mesenteric fat cells in rats. A. Shinoki., and H. Hara. British Journal of Nutrition.Published online :02 June 2011.

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Food restriction improves glucose and lipid metabolism through Sirt1 expression: A study using a new rat model with obesity and severe hypertension. K. Takemori.,T. Kimura.,N. Shirasaka.,T. Inoue.,K. Masuno., and H. Ito. Life Sciences.Vol.88, Issues 25-26, 1088-1094. 2011

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Enhanced Urinary Bladder, Liver and Colon Carcinogenesis in Zucker Diabetic Fatty Rats in a Multiorgan Carcinogenesis Bioassay: Evidence for Mechanisms Involving Activation of PI3K Signaling and Impairment of P53 on Urinary Bladder Carcinogenesis. N. Ishii., M. Wei., A. Kakehashi., K. Doi., S. Yamano., M. Inaba., and H.Wanibuchi. Journal of Toxicologic Pathology .Vol. 24 (2011) , No. 1 pp.25

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Maternal low-protein diet suppresses vascular and renal endothelial nitric oxide synthase phosphorylation in rat offspring independent of a postnatal fructose diet. S. Sato.,Y. Mukai., and T. Norikura. Journal of Developmental Origins of Health and Disease (2011), 2: 168-175

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MS图表例 1

用MALDI-MS检测
少量附加金属物，可得到干净的MS光谱

样支：AngiotensinⅡ(编号No. 019-22931)
基质：CHCA (编号No. 037-19261)

MS图表例 2

(数据提供：日支大阪府立妇幼医疗中心　和田芳直先生)

样支：MS校准混合物
基质：CHCA (编号No. 037-19261)
（※）M.W.755.4107的肽正处于商品化讨论中，同时有胰岛素！

同时有胰岛素！

顺序

产品编号

品名

(M+H)+

包装

1

019-22931

Angiotensin   II (Human)
  MALDI-MS Calibrant

1046.5423

2nmol×1支

015-22933

2nmol×5支

2

017-22971

[D-Arg1,D-Pro2,D-Trp7,9,Leu11]-Substance   P
  MALDI-MS Calibrant

1497.8483

2nmol×1支

013-22973

2nmol×5支

3

016-22941

Apamin
  MALDI-MS Calibrant

2026.8944

2nmol×1支

012-22943

2nmol×5支

4

160-24251

PAMP(Rat)  
  MALDI-MS Calibrant

2477.3642

2nmol×1支

166-24253

2nmol×5支

5

014-22981

ACTH   (Human, 1-24)
  MALDI-MS Calibrant

2932.5885

2nmol×1支

010-22983

2nmol×5支

6

013-22951

Adrenomedullin   (Human,22-52)
  MALDI-MS Calibrant

3574.8770

2nmol×1支

019-22953

2nmol×5支

7

090-05881

Insulin   (Human)
  MALDI-MS Calibrant

5804.6455

2nmol×1支

096-05883

2nmol×5支