Human Stem Cell Derived Cardiomyocytes | ||||||
品牌 | Code No. | 产品名称 | 包装量 | 价格(元) | 说明书 | 数量 |
Cellartis | Y10060 | Cellartis® Pure hES-CM | 1 Kit | ¥14,611 | ||
Cellartis | Y10075 | Cellartis® Cardiomyocytes (from ChiSPC22) Kit | 1 Kit | ¥14,611 |
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人ES细胞来源心肌细胞 (Cardiomyocytes Derived from Human Embryonic Pluripotent Stem Cells) |
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Cellartis Pure Cardiomyocytes (from SA121) 是由基因工程技术改良的人ES细胞株(SA121-cTnT)分化而来的心肌细胞,纯度高(约 90%),可进行维持培养。 | |||||||||||||||||||||||||||
人iPS细胞来源心肌细胞 (Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells) |
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[ 确定Cellartis心肌细胞标志物的表达 ]: | |||||||||||||||||||||||||||
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[Cellartis 心肌细胞的动作电位]: | |||||||||||||||||||||||||||
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1. Synnergren J et al.Molecular signature of cardiomyocyte clusters derived from human embryonic stem cells.Stem Cells 2008 Jul; 26(7): 1831-1840. 2. Jonsson MK et al. Quantified Proarrhythmic Potential of Selected Human Embryonic Stem Cell-derived Cardiomyocytes.Stem Cell Res. 2010 May; 4(3): 189-200. 3. Synnergren J et al. Expression of microRNAs and their target mRNAs in human stem cell derived cardiomyocyte clusters and in heart tissue. Physiol. Genomics 2011 May 1; 43(10): 581-594. 4. Nalos L et al. Comparison of the IKr blockers, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytes.Br. J. Pharmacol. 2012 Jan; 165(2): 467-478. 5. Synnergren J et al. Global transcriptional profiling reveals similarities and differences between human stem cell-derived cardiomyocyte clusters and heart tissue. Physiol. Genomics 2012 Feb 27; 44(4): 245-258. 6. Yamazaki K et al. A novel method of selecting human embryonic stem cell-derived cardiomyocyte clusters for assessment of potential to influence QT interval. Toxicol. In Vitro. 2012 Mar; 26(2): 335-342. 7. Jonsson MK et al. Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG. J. Mol. Cell Cardiol. 2012 May; 52(5): 998-1008. 8. hnke et al. A novel 3D label-free monitoring system of hES-derived cardiomyocyte clusters: a step forward to in vitro cardiotoxicity testing. PLoS One 2013 Jul ;8(7). 9. Yamazaki et al. Beat-to-Beat Variability in Field Potential Duration in Human Embryonic Stem Cell-Derived Cardiomyocyte Clusters for Assessment of Arrhythmogenic Risk, and a Case Study of Its Application. Pharmacol. & Pharm, 2014, 5, 117-128. |
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页面更新:2019-11-25 08:36:03